Forskolin supplement, also referred to as labdane diterpene, is a compound similar to phytol, retinol, retinal and it’s known to be both anti-inflammatory and anti-microbial. It’s produced by Coleus Forskohlii; the Indian Coleus plant that has played a very important role in the Indian traditional forms of medicine for several years. The Coleus Forskohlii plant is a member of the mint plant family and it grows in subtropical areas of Thailand, India and Burma.
Forskolin supplement is also known to activate adenylate cyclase; an enzyme which is involved in regulation of several cellular functions. The enzyme is usually derived from ATP and it is used for the signal transduction in several organisms. The Forskolin extract supplements are also known to cause increases in the cAMP levels which promotes weight loss while also increasing memory formation as well retention more so when used in CILTEP Stack with the Artichoke Extract.
HOW DOES FORSKOLIN SUPPLEMENT WORK?
The main mode of action for the supplement is by activation of adenylate cyclase enzyme. The enzyme is activated by the lipolytic hormones like Adrenaline and Epinephrine. However, Forskolin doesn’t carry similar nervous system effects as compared to these stimulatory hormones. Forskolin works by bypassing the steps that are associated with the unwanted side effects such as restlessness and nervousness. As it is activated, the enzyme converts into cAMP which in turn leads to an increase in the levels of proteins known as kinase and the hormone-sensitive lipase (HSL).
This supplement also works as a vasodilator thus helping in opening up the blood passages. This can increase the flow of blood to the brain thus resulting in better oxygen and nutrient delivery to the brain cells. The neurons in turn might fire more actively thus improving cell maintenance as well.
Forskolin also acts as thyroid stimulants and the supplement acts in a great fashion similar to several conventional asthma treatments. In addition, the cAMP compound serves to relax muscles around bronchial tubes that normally help in making breathing easier.
Forskolin supplement is used as a nootropic in the CILTEP Stack. The supplement stack uses the Forskolin extract as cAMP boosters together with the Artichoke Extract as the PDE-4 inhibitor. The Artichoke Extract prevents breakdown of the excessive cAMP thus allowing users to increase the normal cAMP levels in the brain cells. The end result is a heightened memory performance more so in terms of information retention. Taking Forskolin might also aid in reasoning processes, learning capacity, accessing stored memory as well as improving mental fluidity.
Studies have also shown that Forskolin supplement is beneficial in treating obesity and in weight loss programs. During the study, 30 obese or overweight men using Forskolin achieved greater decreases in body fats and a greater increase in the lean body mass as compared to those in placebo groups. The treatment groups also experienced significant increases in bone mass.
A 2006 study also showed the benefits of the supplement in treating as well as fending off the asthma attacks. This study found out those users of the Forskolin supplement experienced asthma attacks less frequently than the non-users. Furthermore, during the attacks that occurred, the severity was significantly lesser with easier breathing.
Although there’s very little scientific evidences backing this claim, there are people who actually feel Forskolin is helpful in treating glaucoma. The supplement might help in relieving pressure in eyes which is mostly associated with the disease (glaucoma).
Another potential usage of the supplement is in treating some forms of cardiovascular diseases. A few studies have shown that Forskolin help in improving heart functions. People suffering from idiopathic congestive cardiomyopathy might be great candidates for such type of treatment.
The dosage of most Forskolin supplements varies considerably. Generally, you might want to only consider the higher quality supplements which basically means that they ought to contain 10-20% Forskolin. Anything lesser than the said percentage isn’t worth your cash since there’s probably too little of the active ingredients to be effective.
The typical forskolin dosage ranges between 25 to 60 mg daily. This is usually divided between 2 to 3 equal administrations. Most users usually suggest that 50 to 60 mg represents the ideal dosage range for the serious nootropic effects. You might also find it better to take the Forskolin dosages at night since it makes some individuals tired. For best results, one should combine this supplement with 500-900 mg of the artichoke extract daily.
Forskolin has shown to be effective in reducing body fat in overweight and obese users
The supplement might improve fatigue moderately in some instances
The supplement promotes muscle protein synthesis
Forskolin might also improves memory
The supplement has also shown to Increase the cAMP Levels in brain cells
More research required into the cognitive benefits
Might increase the acid levels in the Stomach thus it isn’t recommended for the Individuals suffering from stomach ulcers
Is Forskolin supplement safe for one to use? Conclusive evidences regarding the safety profiles for the forskolin supplement is limited because there has been relatively few studies and tests on it. Although there have been mild reports of side effects, there are few events for people to strictly watch out for. These includes low blood pressure and flushing when taken via an IV, the upper respiratory tract infections, cough, tremor, restlessness when inhaled, headaches and an increased heart rate.
There are also some people who must avoid taking the supplements under all conditions. This includes individuals using anti-platelet and blood thinner medications. Also, there are several high-blood pressure medications which may have interactions with Forskolin. This include things such as beta-blockers, Clonidine, Hydralazine and calcium channel blockers. The supplement must also be avoided by people having kidney diseases as well as breast feeding and pregnant women.
While Forskolin doesn’t have much history of use in nootropic community as compared to the Racetams together with other memory boosters, there are lots of individuals that attest to the effectiveness of this supplement. If you’re interested in trying out the CILTEP stack, you might then have to speak to your own doctor so as to ensure that the supplement is safe for use. One can also purchase the high quality Forskohlii extracts online before taking the supplement on its own or even combine it with Artichoke Extract powders. If you prefer trying cognitive enhancement supplements with more researches behind it, then instead consider using the Racetam stack together with Aniracetam or Piracetam alongside Citicoline or Alpha GPC. These combinations are well-known to be very safe and have been backed up by several positive user reviews online.